{"id":86859,"date":"2024-05-17T14:40:02","date_gmt":"2024-05-17T19:40:02","guid":{"rendered":"https:\/\/mindseyemag.com\/magazine\/?p=86859"},"modified":"2024-05-17T14:40:02","modified_gmt":"2024-05-17T19:40:02","slug":"when-nasa-gave-spiders-drugs-to-see-how-it-affected-their-webs-1995","status":"publish","type":"post","link":"https:\/\/mindseyemag.com\/magazine\/when-nasa-gave-spiders-drugs-to-see-how-it-affected-their-webs-1995\/","title":{"rendered":"When NASA Gave Spiders Drugs To See How It Affected Their Webs, 1995"},"content":{"rendered":"<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-ZLu4xFIFQPw\/YWcw2S7mhQI\/AAAAAAAAf5c\/79Es15jFBWYoNZxVNMy1Baq57l39XDE3QCLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25281%2529.jpg?resize=640%2C427&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"427\" \/><\/p>\n<p class=\"wp-caption-text\">A NASA study from 1995 shows just how different drugs affect the spiders\u2019 ability to make webs.<\/p>\n<\/div>\n<p>A NASA tech briefing\u00a0<em>\u201cUsing Spider-Web Patterns To Determine Toxicity\u201d<\/em>\u00a0was published in April 1995. The work was done by researchers at Marshall Space Flight Center to see how various substances \u2014 including caffeine \u2014 affect spider web patterns.<\/p>\n<p>According to the briefing, the purpose of the study was to examine how toxic a chemical is by exposing spiders to it and comparing how their webs differed from that of a normal spider web.<\/p>\n<p>The researchers exposed spiders to a range of different chemicals, including caffeine, marijuana, and Benzedrine \u2014 a type of amphetamine \u2014 and noted how they spun their webs under the influence of each of those substances. The experiment was performed on European garden spiders.<\/p>\n<p>The article noted:<em>\u00a0\u201cIt appears that one of the most telling measures of toxicity is a decrease, in comparison with a normal web, of the numbers of completed sides in the cells: the greater the toxicity, the more sides the spider fails to complete.\u201d<\/em><\/p>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-Q6hINlBadrg\/YWcw2UUPlKI\/AAAAAAAAf5Y\/qoxvSv5EEvYDo-BAT5eug5lLg_Ov00-mwCLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25282%2529.jpg?resize=640%2C346&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"346\" \/><\/p>\n<p class=\"wp-caption-text\">A web made by a spider on marijuana on the right (normal web is on the left).<\/p>\n<\/div>\n<p>This wasn\u2019t the first time that this kind of experiment was done on spiders. In 1948, Swiss pharmacologist Peter N. Witt started his research on the effect of drugs on spiders.<\/p>\n<p>The initial motivation for the study was a request from his colleague, zoologist H. M. Peters, to shift the time when garden spiders build their webs between 2 a.m. and 5 a.m., which apparently annoyed Peters, to earlier hours.<\/p>\n<p>Witt tested spiders with a range of psychoactive drugs, including amphetamine, mescaline, strychnine, LSD, and caffeine, and found that the drugs affect the size and shape of the web rather than the time when it is built.<\/p>\n<p>At small doses of caffeine (10 \u00b5g\/spider), the webs were smaller; the radii were uneven, but the regularity of the circles was unaffected.<\/p>\n<p>At higher doses (100 \u00b5g\/spider), the shape changed more, and the web design became irregular. All the drugs tested reduced web regularity except for small doses (0.1\u20130.3 \u00b5g) of LSD, which increased web regularity.<\/p>\n<p>The drugs were administered by dissolving them in sugar water, and a drop of solution was touched to the spider\u2019s mouth. In some later studies, spiders were fed with drugged flies.<\/p>\n<p>For qualitative studies, a well-defined volume of solution was administered through a fine syringe. The webs were photographed for the same spider before and after drugging.<\/p>\n<p>NASA\u2019s results were qualitatively similar to those of Witt, but the novelty was that the pattern of the spider web was quantitatively analyzed with modern statistical tools, and proposed as a sensitive method of drug detection.<\/p>\n<p>NASA\u2019s researchers said this approach to toxicity testing could serve as an alternative to testing harmful chemicals on what they referred to as \u201chigher animals,\u201d which they said was \u201cbecoming increasingly restricted by law.\u201d<\/p>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-I941ko4miIY\/YWcw2QnyfHI\/AAAAAAAAf5g\/rhRWUOh-3nE3chbL4HgwlA1z4JC7KHymACLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25283%2529.jpg?resize=640%2C263&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"263\" \/><\/p>\n<p class=\"wp-caption-text\">A normal web on the left next to a web made by a spider on LSD.<\/p>\n<\/div>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-qvGW1ptftfQ\/YWcw2wK8zaI\/AAAAAAAAf5k\/8sdJNp9GTP0iDINCQ5mTCX3rDFN7ufj5ACLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25284%2529.jpg?resize=640%2C354&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"354\" \/><\/p>\n<p class=\"wp-caption-text\">A normal web on the left and a web made by a spider on chloral hydrate (sleeping pills).<\/p>\n<\/div>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-_Wp3OJzpkQg\/YWcw3ACMkCI\/AAAAAAAAf5o\/jiatS725-v0cCT4IWlFmyRYHpKZc4HGQwCLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25285%2529.jpg?resize=640%2C348&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"348\" \/><\/p>\n<p class=\"wp-caption-text\">Spiders who\u2019d sampled caffeine made webs with disorganized cells.<\/p>\n<\/div>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-xJJzh789XvM\/YWcw3qNQVpI\/AAAAAAAAf5s\/Cg28Mx6exPcZ0ecr6UuuRJOiczY1Jw-OQCLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25286%2529.jpg?resize=640%2C356&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"356\" \/><\/p>\n<p class=\"wp-caption-text\">A spider who\u2019d been given Benzedrine spins a deformed web.<\/p>\n<\/div>\n<div class=\"wp-caption aligncenter\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-full\" src=\"https:\/\/i0.wp.com\/1.bp.blogspot.com\/-utpthpUssQQ\/YWcw4PTt--I\/AAAAAAAAf5w\/aMDwgBz-X-o1vNb8coET0QUD6MVu92UJACLcBGAsYHQ\/s1600\/Nasa-spiders-drugs-experiment%2B%25287%2529.jpg?resize=640%2C194&#038;ssl=1\" alt=\"nasa spiders drugs experiment\" width=\"640\" height=\"194\" \/><\/p>\n<p class=\"wp-caption-text\">NASA\u2019s original article.<\/p>\n<\/div>\n<p><em>(Photo credit: NASA \/ Wiki Commons \/ Wikipedia \/ The Sun).<\/em><\/p>\n<p><a href=\"https:\/\/rarehistoricalphotos.com\/nasa-spiders-drugs-experiment\/\"><em><strong>Original Article<\/strong><\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A NASA study from 1995 shows just how different drugs affect the spiders\u2019 ability to<\/p>\n","protected":false},"author":1,"featured_media":86860,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[24],"tags":[],"ppma_author":[800],"class_list":["post-86859","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.6 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>When NASA Gave Spiders Drugs To See How It Affected Their Webs, 1995 ~ Mind&#039;s Eye Mag<\/title>\n<meta name=\"description\" content=\"According to the briefing, 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